ABSTRACT

OBJECTIVE: to estimate the prevalence of HIV and syphilis, and their association with gestational complications and newborn outcomes in women admitted for delivery at a mother and child center in the South of Brazil.
METHODS: cross-sectional study based on the review of electronic medical records of parturients (March/2016 to June/2018). Sociodemographic and clinical data were analyzed. HIV and syphilis were considered outcomes, then exposures to assess associations with pregnancy and neonatal variables. Prevalence Ratio (PR) were calculated using Poisson Regression with robust variance and 95% Confidence Interval (CI).
RESULTS: data from 6,527 women were evaluated. HIV prevalence was 0.6% and syphilis 1.5%. Women assisted by the public health system [PR=2.28 95%CI=1.07-4.82 for syphilis; PR=3.52 95%CI=1.06-11.72 for HIV] and drug users [PR=5.47 95%CI=2.49-12.04 for syphilis; PR=4.76 95%CI=1.12-20.19 for HIV] were more affected. Syphilis was more prevalent among younger and non-white women (p=0.001). Adequate prenatal care reduced syphilis by 38% (PR= 0.62 95%CI=0.39-0.97; p=0.006). Neonatal complications occurred in 32.3% of syphilis cases and 17.1% of HIV cases. Of the 98 syphilis cases, 29.6% led to congenital syphilis.
CONCLUSION: women in socially vulnerable conditions, such as drug users, were more affected. Congenital syphilis exceeded the national average, reinforcing the need for timely and comprehensive prenatal care.

Keywords: Syphilis, HIV seropositive, Congenital syphilis, Sexually transmitted diseases, High-risk pregnancy

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